Anterior proton delivery: handle with care

Proton therapy provides dosimetric benefits over photon-based radiotherapies by reducing the low-dose bath and potentially reducing toxicities. For prostate cancer, however, the overall clinical advantage of proton therapy over modalities such as intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) is unclear – and is the subject of ongoing controversy and clinical investigation