Hypofractionated radiotherapy after breast conserving surgery

The optimal dose and fractionation regimen for whole breast irradiation, whole breast and regional nodal irradiation, and post-mastectomy radiotherapy remains unknown. The goal of this phase II randomised controlled trial is to determine whether the hypofractionated proton regimens proposed are non-inferior compared with standard fractionated proton radiotherapy and therefore worthy of further investigation.

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