Induction chemotherapy followed by intensity-modulated radiotherapy with reduced gross tumour volume delineation for stage T3-4 nasopharyngeal carcinoma

A common problem in stage T3–4 nasopharyngeal carcinoma is the narrow gap between the primary tumour and neurological structures, which makes dose optimisation difficult. Considering that significant tumour shrinkage may occur during induction chemotherapy, this study explored the efficacy of intensity-modulated radiotherapy using reduced gross tumour volume in the treatment of T3–4 nasopharyngeal cancer.
Dove Medical Press