Manganese Dioxide nanoparticles increase tumour vulnerability to radiotherapy

Pretreating tumours with manganese dioxide nanoparticles may increase the efficacy of radiotherapy, according to a new study in mice. Tumors injected with the particles grew less after irradiation than untreated tumors did (ACS Nano 2014, DOI: 10.1021/nn405773r). The nanoparticles react with hydrogen peroxide in the tumors to correct chemical conditions that make tumors aggressive and thwart the effects of radiation.

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