Markers could improve treatment stratification for paediatric medulloblastoma

The use of an intensified treatment regimen to treat metastatic medulloblastoma in children and adolescents conferred an overall favorable survival, according to the results of a recent study. However, patients within varying subgroups and with certain biologic parameters did not have uniform outcomes. Patients in the study were aged between 4 and 21 and diagnosed between 2001 and 2007. All were treated with induction chemotherapy, dose-escalated hyperfractionated craniospinal radiotherapy, and maintenance chemotherapy.
Cancer Network